Portnox + SentinelOne Integration: Out-of-the-Box Endpoint Risk Scoring for a Stronger Zero Trust Posture

In today’s evolving threat landscape, security teams face a constant challenge: how to quickly assess the health of every device trying to access the network – and act accordingly before an incident becomes a breach.
That’s why we’re excited to announce our new, out-of-the-box integration between Portnox and SentinelOne, designed to bring richer endpoint intelligence directly into your access control decisions.

With this integration, Portnox Cloud can now automatically calculate a dynamic risk score for endpoints based on real-time security posture data from SentinelOne. This allows you to make smarter, faster, and more precise zero trust access decisions – without the headaches of manual configuration or custom scripting.

Why This Matters: Zero Trust Starts with Trustworthy Endpoints

Zero Trust is built on a simple principle: never trust, always verify. But to truly verify, you need more than just a device’s IP address or whether it passed a basic antivirus check. You need deep, real-time insight into what’s happening on that endpoint – is it infected, unmanaged, or dormant?

SentinelOne excels at detecting and responding to threats at the endpoint level, using AI-powered prevention, detection, and threat hunting. Portnox excels at enforcing adaptive access policies based on risk. Together, we’ve closed the loop: now, you can automatically incorporate SentinelOne’s findings into Portnox’s access decisions.

How It Works

The Portnox-SentinelOne integration works right out of the box – no complex setup or coding required. Once enabled, Portnox Cloud continuously queries SentinelOne for three key endpoint health indicators:

• Infection Status: If SentinelOne flags an endpoint as infected, Portnox automatically applies a higher risk score to that device. This can trigger automated enforcement actions, such as quarantining the device, restricting network access, or requiring remediation before reconnecting.
• Management Status: Devices not managed by SentinelOne are automatically scored as higher risk. This ensures that rogue, unprotected, or BYOD devices without the SentinelOne agent can’t slip through unnoticed.
• Dormancy Status: If SentinelOne reports that a device has been inactive for an extended period, Portnox can treat it as potentially vulnerable. Dormant devices often miss critical updates, making them attractive targets for attackers once reconnected.

Portnox then incorporates these signals into its dynamic risk policy engine, adjusting each device’s score in real time. These risk scores directly influence your zero trust enforcement policies – allowing only healthy, compliant devices onto your network.

What You Can Do With This Integration

By combining SentinelOne’s endpoint intelligence with Portnox’s access control capabilities, you can:

• Automatically block compromised devices before they connect to critical resources.
• Enforce stricter access controls on unmanaged or dormant devices.
• Trigger remediation workflows – like service restarts, application uninstalls, or patching requirements – before granting access.
• Reduce your attack surface by keeping risky devices off the network until they’re verified safe. This integration also gives you a single, centralized view of both device compliance and endpoint security posture, eliminating blind spots and streamlining your security operations.

The Benefits in Action

Imagine this scenario:

An employee’s laptop is infected with ransomware, and SentinelOne detects the malicious activity. Within seconds, Portnox receives that signal, updates the device’s risk score, and automatically moves it into a quarantine VLAN – stopping the threat from spreading.

Or consider a consultant connecting from a personal laptop without the SentinelOne agent installed. Portnox instantly identifies the device as unmanaged and denies access to sensitive systems until the proper security measures are in place.

That rarely-used conference room PC that hasn’t been powered on in months? If SentinelOne flags it as dormant, Portnox can automatically restrict its access until it’s updated and re-scanned – avoiding a potential “backdoor” for attackers.

Why Out-of-the-Box Matters

Security integrations often promise great results – but only after weeks of custom development, API wrangling, and trial-and-error configuration. We built the Portnox-SentinelOne integration to be ready from day one:

• Quick enablement through Portnox Cloud’s integration settings.
• No coding required – the API connection is already built.

Pre-configured risk scoring rules for infection, management, and dormancy status.

The result? You get the full power of this integration without slowing down your security operations or draining your team’s resources.

A Stronger Zero Trust Foundation

In the zero trust model, every device must earn its place on the network – every time it connects. By combining SentinelOne’s deep endpoint telemetry with Portnox’s adaptive access enforcement, you’re not just checking boxes – you’re actively reducing risk. This isn’t just about stopping known threats. It’s about creating an environment where risky endpoints never get the chance to become security incidents.